Researchers develop self-assembling graphene sensors for modular wearable electronics

Researchers at Peking University, University of Science and Technology Beijing and Peking University Third Hospital have reported magnetically self-assembling graphene sensors. 

While wearable sensors can provide continuous, personalized health tracking beyond clinical visits, most devices today still have fixed designs targeting single applications, lacking versatility to address users' changing needs. The team's recent work could address this issue and enable modular, reconfigurable wearable electronics customized to individuals. 


Balancing suitable electrical properties with biocompatible mechanical characteristics poses many challenges for wearables development. Diagnostic accuracy and versatility improve with precise, adaptable sensors. Yet soft form factors that avoid irritating skin often conflict with adjustable, high-performance components requirements like hard magnets.

Prior reconfigurable wearable attempts usually sacrificed sensing capabilities or interconnection reliability compared to single-use devices due to these trade-offs. But the team's recent study demonstrates magnetic graphene nanocomposites boosting sensor precision while enabling reliable self-assembly – combining the best aspects of both flexible biosensors and customizable electronics.

Graphene’s high conductivity and biocompatibility make it an intriguing base sensing material for skin-mounted electronics. By laser-inducing pores in a graphene film the researchers created a flexible, conductive network well-suited for diverse sensing modalities including electrochemical reactions, electrophysiology signals like ECG, and temperature changes.

The team augmented the sensing film with hard magnetic particles for self-assembly. The resulting “magnetic graphene nanocomposite” (HMGN) drives improvements in sensor performance while enabling reversible, reconfigurable connections. In their experiments, the researchers demonstrated that augmenting the porous graphene film with magnetic particles significantly boosts sensor capabilities. 

Tests showed the magnetic graphene nanocomposite improved sensor precision for metabolites like uric acid and pyridoxine by 70% and cut impedances for electrophysiological sensing by 87% compared to porous graphene alone. For instance, uric acid sensors exhibited sensitivity increasing from 29.6 to 8 nA/µM-1 after magnetic doping. Meanwhile temperature sensors increased their sensitivity from 0.14 to 0.22% °C−1. The magnetically doped graphene also cut impedances for electrophysiological sensing by 87% – from 37.96 kΩ to 4.73 kΩ at 1 kHz frequencies.

Crucially, the magnetic domains allow HMGN films to snap together to form reliable electrical connections without solders or adhesives. Applied magnetic fields organize the haphazard magnetic domains into aligned north-south poles analogous to bar magnets. Opposite poles attract to self-assemble modular HMGN sensors on a flexible substrate into user-defined layouts.

The researchers tested this concept by fabricating an array of 16 impedance-sensing electrodes in HMGN. On command the square electrodes detached and re-assembled into circle and triangle shapes to map damaged tissue geometries. In other experiments swapping single HMGN sensors on a substrate adapted the device sensitivity, spatial coverage and sensing modalities like electrolyte concentrations, ECG signals and temperature.

The team integrated sensors for sodium, chloride and uric acid ions onto a platform to monitor sweat electrolyte loss during exercise. After collecting data the sensors detached so new ones for ECG and temperature could replace them to measure cardiovascular response, demonstrating HMGN’s potential for efficient multifunctional wearable electronics.

Such flexible, modular devices could advance personalized diagnostics and treatments tailored to individual patients and contexts. Continuous tracking of biophysical and biochemical markers outside clinical environments also promises to shift medicine toward preventative care instead of reactive approaches.

Going forward, the team will aim to enhance HMGN’s biocompatibility for more body locations and stretch sensor types to conditions like glucose, humidity and strain. While magnetically self-assembled electronics introduce promising reconfigurability, manual swapping still limits rapid device adaptations to multiple scenarios over short timespans. Fully integrated systems that rearrange modular plug-and-play sensors automatically in response to contextual inputs and usage patterns represent the next frontier.

Posted: Jan 29,2024 by Roni Peleg