Researchers use graphene FET biosensor for simultaneous detection of influenza and SARS-CoV-2
Researchers from University of Texas at Austin have developed an antibody (Ab)-modified graphene field effect transistor (GFET)-based biosensor for precise and rapid influenza A virus (IAV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein detection and differentiation.
The sensor chip that was developed comprised of four GFETs in a quadruple arrangement, separated by polydimethylsiloxane (PDMS) enclosures. Every quarter was biochemically functionalized with SARS-CoV-2 and IAV antigen-targeted Abs, one chemically passivated control, and one bare control. The third (chemically passivated) GFET was deployed to ensure that the results observed were due to Ab-antigen interaction rather than electronic fluctuations or drifts.