A recent study has reported the use of human host defense peptide-conjugated graphene quantum dots for the prevention of virus entry into host cells.
Research on the SARS-CoV-2 virus mainly focuses on the spike protein (S1) which contains the receptor-binding domain (RBD) and the binding of this to the angiotensin converting enzyme 2 (ACE2) receptor within epithelial cells enables the virus to enter host cells in humans. This research resulted in the spike protein becoming a target for vaccines that aimed to produce neutralizing antibodies against the S-RBD. But while this concept seemed useful, recent reports have suggested the mutations on the SARS-CoV-2 virus and specifically in the S-RBD, can cause a decline in the level of neutralizing antibodies against the delta (B.1.617.2) variant that may have been produced during a previous infection or from immunization via a vaccine.